TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice.

Baluk, Peter; Yao, Li-Chin; Feng, Jennifer; Romano, Talia; Jung, Sonia S; Schreiter, Jessica L; Yan, Li; Shealy, David J; McDonald, Donald M

Baluk, Peter; Yao, Li-Chin; Feng, Jennifer; Romano, Talia; Jung, Sonia S; Schreiter, Jessica L; Yan, Li; Shealy, David J; McDonald, Donald M.

Affiliation

Baluk P; Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California-San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA. baluk@ucsf.edu

J Clin Invest ; 119(10): 2954-64, 2009 Oct.

Article in En | MEDLINE | ID: mdl-19759514

Subject(s)

Blood Vessels; Inflammation/immunology; Lymphangiogenesis/immunology; Lymphatic Vessels; Respiratory System; Tumor Necrosis Factor-alpha/immunology; Animals; Blood Vessels/anatomy & histology; Blood Vessels/physiology; Gene Expression Profiling; Glycoproteins/metabolism; Lymphatic Vessels/anatomy & histology; Lymphatic Vessels/physiology; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mycoplasma Infections/immunology; Mycoplasma Infections/pathology; Mycoplasma pulmonis; Platelet Endothelial Cell Adhesion Molecule-1/metabolism; Receptors, Tumor Necrosis Factor, Type I/genetics; Receptors, Tumor Necrosis Factor, Type I/immunology; Receptors, Tumor Necrosis Factor, Type II/genetics; Receptors, Tumor Necrosis Factor, Type II/immunology; Respiratory System/anatomy & histology; Respiratory System/immunology; Signal Transduction/physiology

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Full text: 1 Database: MEDLINE Main subject: Respiratory System / Blood Vessels / Tumor Necrosis Factor-alpha / Lymphatic Vessels / Lymphangiogenesis / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Clin Invest Year: 2009 Type: Article Affiliation country: United States

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