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Intramolecular base-accelerated radical-scavenging reaction of a planar catechin derivative bearing a lysine moiety.
Fukuhara, Kiyoshi; Nakanishi, Ikuo; Ohkubo, Kei; Obara, Yoshinori; Tada, Ayako; Imai, Kohei; Ohno, Akiko; Nakamura, Asao; Ozawa, Toshihiko; Urano, Shiro; Saito, Shinichi; Fukuzumi, Shunichi; Anzai, Kazunori; Miyata, Naoki; Okuda, Haruhiro.
Affiliation
  • Fukuhara K; Division of Organic Chemistry, National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan. fukuhara@nihs.go.jp
Chem Commun (Camb) ; (41): 6180-2, 2009 Nov 07.
Article in En | MEDLINE | ID: mdl-19826661
ABSTRACT
A planar catechin derivative incorporating a lysine moiety was synthesized and showed approximately 400-fold increased radical-scavenging activity relative to naturally-occurring (+)-catechin.
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Full text: 1 Database: MEDLINE Main subject: Catechin / Free Radical Scavengers / Lysine Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2009 Type: Article Affiliation country: Japan
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Full text: 1 Database: MEDLINE Main subject: Catechin / Free Radical Scavengers / Lysine Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2009 Type: Article Affiliation country: Japan