Differences in cytosolic and mitochondrial 5'-nucleotidase and deoxynucleoside kinase activities in Sprague-Dawley rat and CD-1 mouse tissues: implication for the toxicity of nucleoside analogs in animal models.

Mirzaee, Saeedeh; Eriksson, Staffan; Albertioni, Freidoun

Mirzaee, Saeedeh; Eriksson, Staffan; Albertioni, Freidoun.

Affiliation

Mirzaee S; Cancer Center Karolinska Department of Oncology and Pathology, Karolinska University Hospital, SE-17176 Stockholm, Sweden.

Toxicology ; 267(1-3): 159-64, 2010 Jan 12.

Article in En | MEDLINE | ID: mdl-19913594

Subject(s)

5'-Nucleotidase/metabolism; Cytosol/enzymology; Mitochondria/enzymology; Nucleosides/toxicity; Phosphotransferases (Alcohol Group Acceptor)/metabolism; Adipose Tissue/enzymology; Animals; Kidney/enzymology; Liver/enzymology; Male; Mice; Models, Animal; Rats; Rats, Sprague-Dawley; Thymidine Kinase/metabolism

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Full text: 1 Database: MEDLINE Main subject: 5'-Nucleotidase / Phosphotransferases (Alcohol Group Acceptor) / Cytosol / Mitochondria / Nucleosides Limits: Animals Language: En Journal: Toxicology Year: 2010 Type: Article Affiliation country: Sweden

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