PU.1 directly regulates cdk6 gene expression, linking the cell proliferation and differentiation programs in erythroid cells.

Choe, Kevin S; Ujhelly, Olga; Wontakal, Sandeep N; Skoultchi, Arthur I

Choe, Kevin S; Ujhelly, Olga; Wontakal, Sandeep N; Skoultchi, Arthur I.

Affiliation

Choe KS; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

J Biol Chem ; 285(5): 3044-52, 2010 Jan 29.

Article in En | MEDLINE | ID: mdl-19955566

Subject(s)

Cyclin-Dependent Kinase 6/metabolism; Erythroid Cells/cytology; Gene Expression Regulation; Proto-Oncogene Proteins/metabolism; Trans-Activators/metabolism; Animals; Cell Cycle; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Proliferation; GATA1 Transcription Factor/metabolism; Gene Expression Regulation, Neoplastic; Mice; Models, Biological; RNA, Small Interfering/metabolism

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Full text: 1 Database: MEDLINE Main subject: Trans-Activators / Gene Expression Regulation / Proto-Oncogene Proteins / Erythroid Cells / Cyclin-Dependent Kinase 6 Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2010 Type: Article Affiliation country: United States

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