Long human CHGA flanking chromosome 14 sequence required for optimal BAC transgenic "rescue" of disease phenotypes in the mouse Chga knockout.

Vaingankar, Sucheta M; Li, Ying; Corti, Angelo; Biswas, Nilima; Gayen, Jiaur; O'Connor, Daniel T; Mahata, Sushil K

Vaingankar, Sucheta M; Li, Ying; Corti, Angelo; Biswas, Nilima; Gayen, Jiaur; O'Connor, Daniel T; Mahata, Sushil K.

Affiliation

Vaingankar SM; Department of Medicine, University of California at San Diego, San Diego, CA 92093-0838, USA. svaingankar@ucsd.edu

Physiol Genomics ; 41(1): 91-101, 2010 Mar 03.

Article in En | MEDLINE | ID: mdl-20009010

Subject(s)

Chromogranin A/genetics; Chromosomes, Artificial, Bacterial/genetics; Chromosomes, Human, Pair 14/genetics; Adrenal Glands/pathology; Animals; Base Sequence; Blood Pressure; Catecholamines/metabolism; Chromogranin A/deficiency; Chromogranin A/metabolism; Gene Dosage; Gene Expression Regulation; Humans; Mice; Mice, Knockout; Mutagenesis, Insertional/genetics; Phenotype; RNA, Messenger/genetics; RNA, Messenger/metabolism; Restraint, Physical; Stress, Physiological; Transgenes/genetics

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Full text: 1 Database: MEDLINE Main subject: Chromosomes, Human, Pair 14 / Chromosomes, Artificial, Bacterial / Chromogranin A Limits: Animals / Humans Language: En Journal: Physiol Genomics Journal subject: BIOLOGIA MOLECULAR Year: 2010 Type: Article Affiliation country: United States

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