Tuberculosis diagnosed by PCR analysis of synovial fluid.
J Infect Chemother
; 16(1): 53-5, 2010 Feb.
Article
in En
| MEDLINE
| ID: mdl-20052514
ABSTRACT
Tuberculosis is a leading cause of mortality due to an infectious agent worldwide. It often affects multiple organs by hematogenous spread of Mycobacterium tuberculosis, but knee-joint involvement is extremely rare, comprising approximately 0.1% of all forms of tuberculosis. We present a case of tuberculous pleuritis with knee-joint involvement. Cytological and biochemical analysis of the pleural fluid and a biopsy specimen of the cervical lymph node indicated tuberculosis, but a definitive diagnosis was not given. A confirmed diagnosis was finally obtained through PCR analysis of the synovial fluid. Tuberculosis should be included in the differential diagnosis in patients with persistent pain and swelling of the knee. PCR analysis of the synovial fluid is a quick and useful method for the diagnosis.
Full text:
1
Database:
MEDLINE
Main subject:
Synovial Fluid
/
Tuberculosis, Osteoarticular
/
Tuberculosis, Pleural
/
Polymerase Chain Reaction
/
Knee Joint
/
Mycobacterium tuberculosis
Type of study:
Diagnostic_studies
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
J Infect Chemother
Journal subject:
MICROBIOLOGIA
/
TERAPIA POR MEDICAMENTOS
Year:
2010
Type:
Article
Affiliation country:
Japan