Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78.

Misra, U K; Pizzo, S V

Misra, U K; Pizzo, S V.

Affiliation

Misra UK; Department of Pathology, Duke University Medical Center, Box 3712, Durham, NC 27710, USA.

Apoptosis ; 15(2): 173-82, 2010 Feb.

Article in En | MEDLINE | ID: mdl-20091233

Subject(s)

Antibodies/immunology; Antibodies/pharmacology; Heat-Shock Proteins/chemistry; Heat-Shock Proteins/immunology; Prostatic Neoplasms/metabolism; Unfolded Protein Response/drug effects; Apoptosis Regulatory Proteins/metabolism; Bcl-2-Like Protein 11; Caspases/metabolism; Cell Line, Tumor; Down-Regulation/drug effects; Endoplasmic Reticulum/drug effects; Endoplasmic Reticulum/pathology; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation/drug effects; Eukaryotic Initiation Factor-2/metabolism; Humans; Immunoblotting; Male; Membrane Proteins/metabolism; Neoplasm Proteins/metabolism; Poly(ADP-ribose) Polymerases/metabolism; Prostatic Neoplasms/enzymology; Prostatic Neoplasms/pathology; Proto-Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Transcription Factor CHOP/metabolism; Up-Regulation/drug effects; eIF-2 Kinase/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Prostatic Neoplasms / Unfolded Protein Response / Heat-Shock Proteins / Antibodies Type of study: Prognostic_studies Limits: Humans / Male Language: En Journal: Apoptosis Year: 2010 Type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google