Angiotensin-(1-7) stimulates high atrial pacing-induced ANP secretion via Mas/PI3-kinase/Akt axis and Na+/H+ exchanger.

Shah, Amin; Gul, Rukhsana; Yuan, Kuichang; Gao, Shan; Oh, Young-Bin; Kim, Uh-Hyun; Kim, Suhn Hee

Shah, Amin; Gul, Rukhsana; Yuan, Kuichang; Gao, Shan; Oh, Young-Bin; Kim, Uh-Hyun; Kim, Suhn Hee.

Affiliation

Shah A; Department of Physiology, Chonbuk National University Medical School, 2-20 Keum-Am-Dong-San, Jeonju, Korea. shkim@chonbuk.ac.kr

Am J Physiol Heart Circ Physiol ; 298(5): H1365-74, 2010 May.

Article in En | MEDLINE | ID: mdl-20190099

Subject(s)

Angiotensin I/pharmacology; Atrial Natriuretic Factor/metabolism; Cardiac Pacing, Artificial; Peptide Fragments/pharmacology; Phosphatidylinositol 3-Kinases/physiology; Proto-Oncogene Proteins c-akt/physiology; Proto-Oncogene Proteins/physiology; Receptors, G-Protein-Coupled/physiology; Signal Transduction/drug effects; Sodium-Hydrogen Exchangers/metabolism; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism; Cardiotonic Agents/pharmacology; Cyclic GMP/metabolism; In Vitro Techniques; Isoproterenol/pharmacology; Male; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/metabolism; Proto-Oncogene Mas; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor/antagonists & inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Hydrogen Exchangers/drug effects

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Peptide Fragments / Angiotensin I / Cardiac Pacing, Artificial / Signal Transduction / Proto-Oncogene Proteins / Atrial Natriuretic Factor / Sodium-Hydrogen Exchangers / Phosphatidylinositol 3-Kinases / Receptors, G-Protein-Coupled / Proto-Oncogene Proteins c-akt Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2010 Type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google