Production of an antigenic peptide by insulin-degrading enzyme.

Parmentier, Nicolas; Stroobant, Vincent; Colau, Didier; de Diesbach, Philippe; Morel, Sandra; Chapiro, Jacques; van Endert, Peter; Van den Eynde, Benoît J

Parmentier, Nicolas; Stroobant, Vincent; Colau, Didier; de Diesbach, Philippe; Morel, Sandra; Chapiro, Jacques; van Endert, Peter; Van den Eynde, Benoît J.

Affiliation

Parmentier N; Ludwig Institute for Cancer Research, Brussels Branch, Brussels, Belgium.

Nat Immunol ; 11(5): 449-54, 2010 May.

Article in En | MEDLINE | ID: mdl-20364150

Subject(s)

Antigen Presentation; Antigens, Neoplasm/metabolism; Insulysin/metabolism; Neoplasm Proteins/metabolism; Peptide Fragments/metabolism; T-Lymphocytes, Cytotoxic/metabolism; Antibodies, Blocking/pharmacology; Antigen Presentation/drug effects; Antigen Presentation/genetics; Antigens, Neoplasm/immunology; Cell Fractionation; Cell Line, Tumor; Chromatography, High Pressure Liquid; Clone Cells; Cytosol; Glycopeptides/pharmacology; HLA-A1 Antigen/metabolism; Humans; Insulysin/genetics; Insulysin/immunology; Interferon-gamma/metabolism; Mass Spectrometry; Metalloendopeptidases/antagonists & inhibitors; Neoplasm Proteins/immunology; Oligopeptides/pharmacology; Peptide Fragments/immunology; Phenanthrolines/pharmacology; Proteasome Inhibitors; RNA, Small Interfering/genetics; T-Lymphocytes, Cytotoxic/immunology; T-Lymphocytes, Cytotoxic/pathology

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Full text: 1 Database: MEDLINE Main subject: Peptide Fragments / T-Lymphocytes, Cytotoxic / Antigen Presentation / Insulysin / Antigens, Neoplasm / Neoplasm Proteins Limits: Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2010 Type: Article Affiliation country: Belgium

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