Targeted cancer therapy with novel high drug-loading nanocrystals.

Liu, Feng; Park, Ji-Young; Zhang, Yong; Conwell, Christine; Liu, Yang; Bathula, Surendar Reddy; Huang, Leaf

Liu, Feng; Park, Ji-Young; Zhang, Yong; Conwell, Christine; Liu, Yang; Bathula, Surendar Reddy; Huang, Leaf.

Affiliation

Liu F; Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7360, USA. fliu@email.unc.edu

J Pharm Sci ; 99(8): 3542-51, 2010 Aug.

Article in En | MEDLINE | ID: mdl-20564383

Subject(s)

Antineoplastic Agents/administration & dosage; Antineoplastic Agents/therapeutic use; Neoplasms/drug therapy; Animals; Antineoplastic Agents/toxicity; Antineoplastic Agents, Phytogenic/administration & dosage; Camptothecin/administration & dosage; Carrier Proteins/drug effects; Chemistry, Pharmaceutical; Drug Delivery Systems; Excipients; Female; Folate Receptors, GPI-Anchored; Glycerol/analogs & derivatives; Hemolysis/drug effects; Humans; Lung Neoplasms/drug therapy; Mammary Neoplasms, Experimental/drug therapy; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Nanoparticles; Neoplasm Transplantation; Paclitaxel/administration & dosage; Poloxamer; Receptors, Cell Surface/drug effects; Surface-Active Agents

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Full text: 1 Database: MEDLINE Main subject: Neoplasms / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: J Pharm Sci Year: 2010 Type: Article Affiliation country: United States

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