Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response.

Kiyotani, Kazuma; Mushiroda, Taisei; Hosono, Naoya; Tsunoda, Tatsuhiko; Kubo, Michiaki; Aki, Fuminori; Okazaki, Yutaka; Hirata, Koichi; Takatsuka, Yuichi; Okazaki, Minoru; Ohsumi, Shozo; Yamakawa, Takashi; Sasa, Mitsunori; Nakamura, Yusuke; Zembutsu, Hitoshi

Kiyotani, Kazuma; Mushiroda, Taisei; Hosono, Naoya; Tsunoda, Tatsuhiko; Kubo, Michiaki; Aki, Fuminori; Okazaki, Yutaka; Hirata, Koichi; Takatsuka, Yuichi; Okazaki, Minoru; Ohsumi, Shozo; Yamakawa, Takashi; Sasa, Mitsunori; Nakamura, Yusuke; Zembutsu, Hitoshi.

Affiliation

Kiyotani K; Laboratory for Pharmacogenetics, RIKEN Center for Genomic Medicine, Yokohama, Japan.

Pharmacogenet Genomics ; 20(9): 565-8, 2010 Sep.

Article in En | MEDLINE | ID: mdl-20574415

Subject(s)

Cytochrome P-450 CYP2D6/genetics; Genetic Association Studies; Pharmacogenetics; Tamoxifen/therapeutic use; Breast Neoplasms/drug therapy; Breast Neoplasms/enzymology; Breast Neoplasms/genetics; Female; Gene Frequency/genetics; Genotype; Humans; Kaplan-Meier Estimate; Proportional Hazards Models

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Full text: 1 Database: MEDLINE Main subject: Pharmacogenetics / Tamoxifen / Cytochrome P-450 CYP2D6 / Genetic Association Studies Type of study: Prognostic_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: Pharmacogenet Genomics Journal subject: FARMACOLOGIA / GENETICA MEDICA Year: 2010 Type: Article Affiliation country: Japan

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