Lipidomics: coming to grips with lipid diversity.
Nat Rev Mol Cell Biol
; 11(8): 593-8, 2010 08.
Article
in En
| MEDLINE
| ID: mdl-20606693
ABSTRACT
Although lipids are biomolecules with seemingly simple chemical structures, the molecular composition of the cellular lipidome is complex and, currently, poorly understood. The exact mechanisms of how compositional complexity affects cell homeostasis and its regulation also remain unclear. This emerging field is developing sensitive mass spectrometry technologies for the quantitative characterization of the lipidome. Here, we argue that lipidomics will become an essential tool kit in cell and developmental biology, molecular medicine and nutrition.
Full text:
1
Database:
MEDLINE
Main subject:
Lipid Metabolism
/
Lipids
Type of study:
Etiology_studies
Limits:
Humans
Language:
En
Journal:
Nat Rev Mol Cell Biol
Journal subject:
BIOLOGIA MOLECULAR
Year:
2010
Type:
Article
Affiliation country:
Germany