Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.

Wang, Hui; Morita, Masahiro; Yang, Xiuna; Suzuki, Toru; Yang, Wen; Wang, Jiao; Ito, Kentaro; Wang, Quan; Zhao, Cong; Bartlam, Mark; Yamamoto, Tadashi; Rao, Zihe

Wang, Hui; Morita, Masahiro; Yang, Xiuna; Suzuki, Toru; Yang, Wen; Wang, Jiao; Ito, Kentaro; Wang, Quan; Zhao, Cong; Bartlam, Mark; Yamamoto, Tadashi; Rao, Zihe.

Affiliation

Wang H; Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, PR China.

EMBO J ; 29(15): 2566-76, 2010 Aug 04.

Article in En | MEDLINE | ID: mdl-20628353

Subject(s)

Poly A/chemistry; Poly A/metabolism; Ribonucleases/chemistry; Ribonucleases/metabolism; Biocatalysis; Crystallography, X-Ray; DNA, Single-Stranded/metabolism; Humans; Magnesium/metabolism; Models, Molecular; Nucleic Acid Conformation; Protein Binding; Protein Structure, Tertiary; Ribonucleases/genetics; Substrate Specificity

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Full text: 1 Database: MEDLINE Main subject: Poly A / Ribonucleases Limits: Humans Language: En Journal: EMBO J Year: 2010 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Poly A / Ribonucleases Limits: Humans Language: En Journal: EMBO J Year: 2010 Type: Article