NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome.

Hölzel, Michael; Huang, Sidong; Koster, Jan; Ora, Ingrid; Lakeman, Arjan; Caron, Huib; Nijkamp, Wouter; Xie, Jing; Callens, Tom; Asgharzadeh, Shahab; Seeger, Robert C; Messiaen, Ludwine; Versteeg, Rogier; Bernards, René

Hölzel, Michael; Huang, Sidong; Koster, Jan; Ora, Ingrid; Lakeman, Arjan; Caron, Huib; Nijkamp, Wouter; Xie, Jing; Callens, Tom; Asgharzadeh, Shahab; Seeger, Robert C; Messiaen, Ludwine; Versteeg, Rogier; Bernards, René.

Affiliation

Hölzel M; Divisions of Molecular Carcinogenesis and Molecular Genetics, Center for Biomedical Genetics and Cancer Genomics Center, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Cell ; 142(2): 218-29, 2010 Jul 23.

Article in En | MEDLINE | ID: mdl-20655465

Subject(s)

Neuroblastoma/diagnosis; Neurofibromin 1/metabolism; Tretinoin/metabolism; Cell Line, Tumor; DNA-Binding Proteins/metabolism; Humans; Neuroblastoma/metabolism; Neurofibromin 1/genetics; Prognosis; Proteins; Signal Transduction; Transcriptional Activation

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Full text: 1 Database: MEDLINE Main subject: Tretinoin / Neurofibromin 1 / Neuroblastoma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Year: 2010 Type: Article Affiliation country: Netherlands

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