The biological effects of C/EBPalpha in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain.

Ferrari-Amorotti, Giovanna; Mariani, Samanta Antonella; Novi, Chiara; Cattelani, Sara; Pecorari, Luisa; Corradini, Francesca; Soliera, Angela Rachele; Manzotti, Gloria; Fragliasso, Valentina; Zhang, Ying; Martinez, Robert V; Lam, Eric W-F; Guerzoni, Clara; Calabretta, Bruno

Ferrari-Amorotti, Giovanna; Mariani, Samanta Antonella; Novi, Chiara; Cattelani, Sara; Pecorari, Luisa; Corradini, Francesca; Soliera, Angela Rachele; Manzotti, Gloria; Fragliasso, Valentina; Zhang, Ying; Martinez, Robert V; Lam, Eric W-F; Guerzoni, Clara; Calabretta, Bruno.

Affiliation

Ferrari-Amorotti G; Department of Biological Sciences, University of Modena and Reggio Emilia, 41100 Modena, Italy.

J Biol Chem ; 285(40): 30837-50, 2010 Oct 01.

Article in En | MEDLINE | ID: mdl-20659895

Subject(s)

CCAAT-Enhancer-Binding Proteins/metabolism; Cell Cycle; Gene Expression Regulation; Promoter Regions, Genetic; Transcription, Genetic; Apoptosis/genetics; CCAAT-Enhancer-Binding Protein-beta/genetics; CCAAT-Enhancer-Binding Protein-beta/metabolism; CCAAT-Enhancer-Binding Proteins/genetics; Cell Differentiation/genetics; Forkhead Box Protein O3; Forkhead Transcription Factors/biosynthesis; Forkhead Transcription Factors/genetics; Granulocyte Colony-Stimulating Factor/biosynthesis; Granulocyte Colony-Stimulating Factor/genetics; Humans; K562 Cells; Protein Structure, Tertiary; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism

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Full text: 1 Database: MEDLINE Main subject: Transcription, Genetic / Cell Cycle / Gene Expression Regulation / Promoter Regions, Genetic / CCAAT-Enhancer-Binding Proteins Limits: Humans Language: En Journal: J Biol Chem Year: 2010 Type: Article Affiliation country: Italy

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