The prion protein as a receptor for amyloid-beta.

Kessels, Helmut W; Nguyen, Louis N; Nabavi, Sadegh; Malinow, Roberto

Kessels, Helmut W; Nguyen, Louis N; Nabavi, Sadegh; Malinow, Roberto.

Affiliation

Kessels HW; Center for Neural Circuits and Behavior, 9500 Gilman Drive 0634, University of California at San Diego, La Jolla, California 92093, USA.

Nature ; 466(7308): E3-4; discussion E4-5, 2010 Aug 12.

Article in En | MEDLINE | ID: mdl-20703260

Subject(s)

Amyloid beta-Peptides/metabolism; PrPC Proteins/metabolism; Synapses/metabolism; Synapses/pathology; Alzheimer Disease/metabolism; Alzheimer Disease/pathology; Amyloid beta-Peptides/chemistry; Amyloid beta-Peptides/genetics; Animals; Learning/physiology; Mice; Mice, Inbred C57BL; Mice, Transgenic; PrPC Proteins/deficiency; PrPC Proteins/genetics; Reproducibility of Results; Serotonin/metabolism; Synaptic Transmission

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Full text: 1 Database: MEDLINE Main subject: Synapses / Amyloid beta-Peptides / PrPC Proteins Limits: Animals Language: En Journal: Nature Year: 2010 Type: Article Affiliation country: United States

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