Recombinant EDA or Sonic Hedgehog rescue the branching defect in Ectodysplasin A pathway mutant salivary glands in vitro.

Wells, K L; Mou, C; Headon, D J; Tucker, A S

Wells, K L; Mou, C; Headon, D J; Tucker, A S.

Affiliation

Wells KL; Department of Craniofacial Development, Dental Institute, King's College London, London, United Kingdom.

Dev Dyn ; 239(10): 2674-84, 2010 Oct.

Article in En | MEDLINE | ID: mdl-20803597

Subject(s)

Ectodysplasins/metabolism; Hedgehog Proteins/metabolism; Salivary Glands/metabolism; Animals; Ectodysplasins/genetics; Edar Receptor/genetics; Edar Receptor/metabolism; Edar-Associated Death Domain Protein/genetics; Edar-Associated Death Domain Protein/metabolism; Genotype; Hedgehog Proteins/genetics; In Situ Hybridization; Mice; Mice, Mutant Strains; Morphogenesis/genetics; Morphogenesis/physiology; Organ Culture Techniques; Salivary Glands/embryology; Signal Transduction/genetics; Signal Transduction/physiology

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Full text: 1 Database: MEDLINE Main subject: Salivary Glands / Ectodysplasins / Hedgehog Proteins Limits: Animals Language: En Journal: Dev Dyn Journal subject: ANATOMIA Year: 2010 Type: Article Affiliation country: United kingdom

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