The effect of immobilization of heparin and bone morphogenic protein-2 (BMP-2) to titanium surfaces on inflammation and osteoblast function.

Kim, Sung Eun; Song, Sang-Hun; Yun, Young Pil; Choi, Byung-Joon; Kwon, Il Keun; Bae, Min Soo; Moon, Ho-Jin; Kwon, Yong-Dae

Kim, Sung Eun; Song, Sang-Hun; Yun, Young Pil; Choi, Byung-Joon; Kwon, Il Keun; Bae, Min Soo; Moon, Ho-Jin; Kwon, Yong-Dae.

Affiliation

Kim SE; Department of Orthopedic Surgery and Rare Diseases Institute, Korea University Medical College, Guro Hospital, Seoul, Korea.

Biomaterials ; 32(2): 366-73, 2011 Jan.

Article in En | MEDLINE | ID: mdl-20880582

Subject(s)

Bone Morphogenetic Protein 2/immunology; Bone Morphogenetic Protein 2/pharmacology; Heparin/immunology; Heparin/pharmacology; Osteoblasts/metabolism; Titanium/chemistry; Alkaline Phosphatase/metabolism; Animals; Bone Morphogenetic Protein 2/chemistry; Calcium/metabolism; Cell Line; Cell Line, Tumor; Cell Proliferation/drug effects; Heparin/chemistry; Humans; Interleukin-6/genetics; Macrophages/drug effects; Macrophages/metabolism; Mice; Microscopy, Electron, Scanning; NIH 3T3 Cells; Osteoblasts/cytology; Osteoblasts/drug effects; Photoelectron Spectroscopy; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha/genetics

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Full text: 1 Database: MEDLINE Main subject: Osteoblasts / Titanium / Heparin / Bone Morphogenetic Protein 2 Limits: Animals / Humans Language: En Journal: Biomaterials Year: 2011 Type: Article

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