A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma.

Nghiemphu, Phioanh Leia; Wen, Patrick Y; Lamborn, Kathleen R; Drappatz, Jan; Robins, H Ian; Fink, Karen; Malkin, Mark G; Lieberman, Frank S; DeAngelis, Lisa M; Torres-Trejo, Alejandro; Chang, Susan M; Abrey, Lauren; Fine, Howard A; Demopoulos, Alexis; Lassman, Andrew B; Kesari, Santosh; Mehta, Minesh P; Prados, Michael D; Cloughesy, Timothy F

Nghiemphu, Phioanh Leia; Wen, Patrick Y; Lamborn, Kathleen R; Drappatz, Jan; Robins, H Ian; Fink, Karen; Malkin, Mark G; Lieberman, Frank S; DeAngelis, Lisa M; Torres-Trejo, Alejandro; Chang, Susan M; Abrey, Lauren; Fine, Howard A; Demopoulos, Alexis; Lassman, Andrew B; Kesari, Santosh; Mehta, Minesh P; Prados, Michael D; Cloughesy, Timothy F.

Affiliation

Nghiemphu PL; University of California, Los Angeles, CA 90095, USA. leian@ucla.edu

Int J Radiat Oncol Biol Phys ; 81(5): 1422-7, 2011 Dec 01.

Article in En | MEDLINE | ID: mdl-20934264

Subject(s)

Antineoplastic Agents/administration & dosage; Brain Neoplasms/therapy; Chemoradiotherapy/methods; Dacarbazine/analogs & derivatives; Glioblastoma/therapy; Quinolones/administration & dosage; Adult; Aged; Antineoplastic Agents/adverse effects; Antineoplastic Combined Chemotherapy Protocols/adverse effects; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Dacarbazine/administration & dosage; Dacarbazine/adverse effects; Female; Humans; Male; Middle Aged; Quinolones/adverse effects; Temozolomide

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Full text: 1 Database: MEDLINE Main subject: Brain Neoplasms / Glioblastoma / Quinolones / Dacarbazine / Chemoradiotherapy / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Int J Radiat Oncol Biol Phys Year: 2011 Type: Article Affiliation country: United States

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