The CDR-H3 repertoire from TdT-deficient adult bone marrow is a close, but not exact, homologue of the CDR-H3 repertoire from perinatal liver.

Schelonka, Robert L; Ivanov, Ivaylo I; Vale, Andre M; Szymanska, Ewa; Zemlin, Michael; Gartland, G Larry; Schroeder, Harry W

Schelonka, Robert L; Ivanov, Ivaylo I; Vale, Andre M; Szymanska, Ewa; Zemlin, Michael; Gartland, G Larry; Schroeder, Harry W.

Affiliation

Schelonka RL; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

J Immunol ; 185(10): 6075-84, 2010 Nov 15.

Article in En | MEDLINE | ID: mdl-20956348

Subject(s)

Bone Marrow/immunology; Complementarity Determining Regions/genetics; DNA Nucleotidylexotransferase/deficiency; Liver/immunology; Precursor Cells, B-Lymphoid/immunology; Amino Acid Sequence; Animals; B-Lymphocytes/chemistry; B-Lymphocytes/immunology; Cell Separation; Complementarity Determining Regions/chemistry; Complementarity Determining Regions/immunology; Flow Cytometry; Immunoglobulin Heavy Chains/chemistry; Immunoglobulin Heavy Chains/immunology; Liver/cytology; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Precursor Cells, B-Lymphoid/chemistry; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Database: MEDLINE Main subject: Bone Marrow / Complementarity Determining Regions / DNA Nucleotidylexotransferase / Precursor Cells, B-Lymphoid / Liver Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunol Year: 2010 Type: Article Affiliation country: United States

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