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Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.
Mrkonjic, Miralem; Roslin, Nicole M; Greenwood, Celia M; Raptis, Stavroula; Pollett, Aaron; Laird, Peter W; Pethe, Vaijayanti V; Chiang, Theodore; Daftary, Darshana; Dicks, Elizabeth; Thibodeau, Stephen N; Gallinger, Steven; Parfrey, Patrick S; Younghusband, H Banfield; Potter, John D; Hudson, Thomas J; McLaughlin, John R; Green, Roger C; Zanke, Brent W; Newcomb, Polly A; Paterson, Andrew D; Bapat, Bharati.
Affiliation
  • Mrkonjic M; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
PLoS One ; 5(10): e13314, 2010 Oct 13.
Article in En | MEDLINE | ID: mdl-20967208
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Full text: 1 Database: MEDLINE Main subject: Nuclear Proteins / Colorectal Neoplasms / Microsatellite Repeats / DNA Methylation / Adaptor Proteins, Signal Transducing Type of study: Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2010 Type: Article Affiliation country: Canada
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Full text: 1 Database: MEDLINE Main subject: Nuclear Proteins / Colorectal Neoplasms / Microsatellite Repeats / DNA Methylation / Adaptor Proteins, Signal Transducing Type of study: Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2010 Type: Article Affiliation country: Canada