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Long-term recurrence rates following dilation of symptomatic Schatzki rings.
Müller, Michaela; Gockel, Ines; König, Jochem; Kuhr, Kathrin; Eckardt, Volker F.
Affiliation
  • Müller M; Department of Gastroenterology, Deutsche Klinik für Diagnostik, Aukammallee 33, 65191, Wiesbaden, Germany. mueller.gastro@dkd-wiesbaden.de
Dig Dis Sci ; 56(5): 1432-7, 2011 May.
Article in En | MEDLINE | ID: mdl-20976623
ABSTRACT
BACKGROUND AND

AIMS:

This study investigated the long-term clinical course of patients with Schatzki rings, who were treated by single bougie dilation. Furthermore, it analyzed possible predictors for the time of recurrence. PATIENTS AND

METHODS:

A total of 133 patients (100 males, 33 females) with a mean age of 57 ± 14.6 years who were treated by single dilation with the use of Maloney bougies without the aid of fluoroscopy were prospectively registered and followed-up for a mean duration of 58.3 months (range 12-240 months). Duration of remission was evaluated by Kaplan-Meier estimates with regard to recurrence. Log-rank test was performed to analyze possible predictors for the time to second dilation (recurrence).

RESULTS:

No complications occurred and all patients were symptom-free at the first follow-up examination 4 weeks after dilation. However, later on, 73 patients required a second dilation. The estimate remission rates were 63.8% (95% CI 55.6-72.0%) after 2 years, 44.3% (95% CI 35.4-53.4%) after 5 years, and 39.9% (95% CI 30.5-49.3%) after 10 years. Neither the initial morphological findings, nor age or gender determined the need for repeated dilation. Only patients treated with a large bougie diameter (≥52 F) seemed to have a tendency for a longer time until symptomatic recurrence.

CONCLUSIONS:

Single dilation of symptomatic Schatzki rings is a safe and effective therapy. However, more than half of the patients will need a second treatment. Recurrences are unrelated to initial morphological findings, age, or gender. Only the treatment with a large bougie diameter (≥52 F) showed a tendency for a longer time of remission.
Subject(s)

Full text: 1 Database: MEDLINE Main subject: Dilatation / Esophageal Stenosis / Esophagogastric Junction Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Dig Dis Sci Year: 2011 Type: Article Affiliation country: Germany

Full text: 1 Database: MEDLINE Main subject: Dilatation / Esophageal Stenosis / Esophagogastric Junction Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Dig Dis Sci Year: 2011 Type: Article Affiliation country: Germany