Re and Tc tricarbonyl complexes: from the suppression of NO biosynthesis in macrophages to in vivo targeting of inducible nitric oxide synthase.

Oliveira, Bruno L; Raposinho, Paula D; Mendes, Filipa; Figueira, Flávio; Santos, Isabel; Ferreira, António; Cordeiro, Carlos; Freire, Ana P; Correia, João D G

Oliveira, Bruno L; Raposinho, Paula D; Mendes, Filipa; Figueira, Flávio; Santos, Isabel; Ferreira, António; Cordeiro, Carlos; Freire, Ana P; Correia, João D G.

Affiliation

Oliveira BL; Unidade de Ciências Químicas e Radiofarmacêuticas, ITN, Estrada Nacional 10, 2686-953 Sacavém, Portugal.

Bioconjug Chem ; 21(12): 2168-72, 2010 Dec 15.

Article in En | MEDLINE | ID: mdl-21043515

Subject(s)

Coordination Complexes/pharmacokinetics; Macrophages/enzymology; Molecular Probes/pharmacokinetics; Nitric Oxide Synthase Type II; Animals; Arginine/metabolism; Cell Line, Tumor; Cell Membrane Permeability; Citrulline/metabolism; Coordination Complexes/chemistry; Enzyme Inhibitors/pharmacology; Female; Lipopolysaccharides/pharmacology; Macrophages/cytology; Macrophages/drug effects; Mice; Mice, Inbred C57BL; Molecular Probes/chemistry; Nitric Oxide/metabolism; Nitric Oxide Synthase Type II/antagonists & inhibitors; Nitric Oxide Synthase Type II/metabolism; Organ Specificity; Rhenium/metabolism; Technetium/metabolism; Tissue Distribution

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Molecular Probes / Nitric Oxide Synthase Type II / Coordination Complexes / Macrophages Type of study: Prognostic_studies Limits: Animals Language: En Journal: Bioconjug Chem Journal subject: BIOQUIMICA Year: 2010 Type: Article Affiliation country: Portugal

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google