Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.

Ikram, M Kamran; Sim, Xueling; Xueling, Sim; Jensen, Richard A; Cotch, Mary Frances; Hewitt, Alex W; Ikram, M Arfan; Wang, Jie Jin; Klein, Ronald; Klein, Barbara E K; Breteler, Monique M B; Cheung, Ning; Liew, Gerald; Mitchell, Paul; Uitterlinden, Andre G; Rivadeneira, Fernando; Hofman, Albert; de Jong, Paulus T V M; van Duijn, Cornelia M; Kao, Linda; Cheng, Ching-Yu; Smith, Albert Vernon; Glazer, Nicole L; Lumley, Thomas; McKnight, Barbara; Psaty, Bruce M; Jonasson, Fridbert; Eiriksdottir, Gudny; Aspelund, Thor; Harris, Tamara B; Launer, Lenore J; Taylor, Kent D; Li, Xiaohui; Iyengar, Sudha K; Xi, Quansheng; Sivakumaran, Theru A; Mackey, David A; Macgregor, Stuart; Martin, Nicholas G; Young, Terri L; Bis, Josh C; Wiggins, Kerri L; Heckbert, Susan R; Hammond, Christopher J; Andrew, Toby; Fahy, Samantha; Attia, John; Holliday, Elizabeth G; Scott, Rodney J; Islam, F M Amirul

Ikram, M Kamran; Sim, Xueling; Xueling, Sim; Jensen, Richard A; Cotch, Mary Frances; Hewitt, Alex W; Ikram, M Arfan; Wang, Jie Jin; Klein, Ronald; Klein, Barbara E K; Breteler, Monique M B; Cheung, Ning; Liew, Gerald; Mitchell, Paul; Uitterlinden, Andre G; Rivadeneira, Fernando; Hofman, Albert; de Jong, Paulus T V M; van Duijn, Cornelia M; Kao, Linda; Cheng, Ching-Yu; Smith, Albert Vernon; Glazer, Nicole L; Lumley, Thomas; McKnight, Barbara; Psaty, Bruce M; Jonasson, Fridbert; Eiriksdottir, Gudny; Aspelund, Thor; Harris, Tamara B; Launer, Lenore J; Taylor, Kent D; Li, Xiaohui; Iyengar, Sudha K; Xi, Quansheng; Sivakumaran, Theru A; Mackey, David A; Macgregor, Stuart; Martin, Nicholas G; Young, Terri L; Bis, Josh C; Wiggins, Kerri L; Heckbert, Susan R; Hammond, Christopher J; Andrew, Toby; Fahy, Samantha; Attia, John; Holliday, Elizabeth G; Scott, Rodney J; Islam, F M Amirul.

Affiliation

Ikram MK; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.

PLoS Genet ; 6(10): e1001184, 2010 Oct 28.

Article in En | MEDLINE | ID: mdl-21060863

Subject(s)

Genetic Loci/genetics; Genome-Wide Association Study/methods; Microcirculation; Polymorphism, Single Nucleotide; Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases/genetics; Cardiovascular Diseases/physiopathology; Child; Child, Preschool; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 19; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 6; Cohort Studies; Female; Humans; Male; Meta-Analysis as Topic; Middle Aged; Retinal Vessels/physiopathology; White People/genetics; Young Adult

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Full text: 1 Database: MEDLINE Main subject: Polymorphism, Single Nucleotide / Genome-Wide Association Study / Genetic Loci / Microcirculation Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Male / Middle aged Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2010 Type: Article Affiliation country: Netherlands

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