The MG-QOL15 for following the health-related quality of life of patients with myasthenia gravis.
Muscle Nerve
; 43(1): 14-8, 2011 Jan.
Article
in En
| MEDLINE
| ID: mdl-21082698
ABSTRACT
The MG-QOL15 is helpful in informing the clinician about the patient's perception of the extent of and dissatisfaction with myasthenia gravis (MG)-related dysfunction. The aims of this study were to determine the usefulness of the MG-QOL15 for following individuals with MG and to guide clinical researchers who plan to use the MG-QOL15. We assessed sensitivity and specificity for detecting clinical change and evaluated test-retest reliability. Sensitivities and specificities of various cut-points of change in scores are presented. Also presented are means and standard deviations of MG-QOL15 scores for all patients and for subgroups of patients. The test-retest reliability coefficient was 98.6%. The MG-QOL15 has an acceptable longitudinal construct validity. We consider this instrument to be most useful for informing the clinician about the patient's perception and tolerance of MG-related dysfunction. More objective measures, such as the MG Composite, should also be used to follow disease severity.
Full text:
1
Database:
MEDLINE
Main subject:
Quality of Life
/
Health Status
/
Mental Health
/
Surveys and Questionnaires
/
Health Surveys
/
Myasthenia Gravis
Type of study:
Clinical_trials
/
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Muscle Nerve
Year:
2011
Type:
Article
Affiliation country:
United States