Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology.

Yuraszeck, Theresa M; Neveu, Pierre; Rodriguez-Fernandez, Maria; Robinson, Anne; Kosik, Kenneth S; Doyle, Francis J

Yuraszeck, Theresa M; Neveu, Pierre; Rodriguez-Fernandez, Maria; Robinson, Anne; Kosik, Kenneth S; Doyle, Francis J.

Affiliation

Yuraszeck TM; Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California, USA.

PLoS Comput Biol ; 6(11): e1000997, 2010 Nov 11.

Article in En | MEDLINE | ID: mdl-21085645

Subject(s)

Models, Biological; Systems Biology/methods; tau Proteins/physiology; Alzheimer Disease/metabolism; Animals; Brain Chemistry; COS Cells; Chlorocebus aethiops; Computer Simulation; Humans; Protein Conformation; Reproducibility of Results; Signal Transduction; tau Proteins/chemistry; tau Proteins/metabolism

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Full text: 1 Database: MEDLINE Main subject: Tau Proteins / Systems Biology / Models, Biological Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS Comput Biol Journal subject: BIOLOGIA / INFORMATICA MEDICA Year: 2010 Type: Article Affiliation country: United States

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