A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner.

Bertelsen, Vibeke; Sak, Malgorzata Magdalena; Breen, Kamilla; Rødland, Marianne S; Johannessen, Lene E; Traub, Linton M; Stang, Espen; Madshus, Inger Helene

Bertelsen, Vibeke; Sak, Malgorzata Magdalena; Breen, Kamilla; Rødland, Marianne S; Johannessen, Lene E; Traub, Linton M; Stang, Espen; Madshus, Inger Helene.

Affiliation

Bertelsen V; Institute of Pathology, Faculty of Medicine, University of Oslo, 0027 Oslo, Norway.

Traffic ; 12(4): 507-20, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21226813

Subject(s)

Clathrin/metabolism; ErbB Receptors/metabolism; Recombinant Fusion Proteins/metabolism; Adaptor Proteins, Vesicular Transport/metabolism; Cells, Cultured; Coated Pits, Cell-Membrane/metabolism; Endocytosis/physiology; Endosomes/metabolism; Epidermal Growth Factor/metabolism; ErbB Receptors/genetics; Gene Knockout Techniques; HeLa Cells; Humans; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-cbl/genetics; Proto-Oncogene Proteins c-cbl/metabolism; RNA, Small Interfering/administration & dosage; RNA, Small Interfering/genetics; Recombinant Fusion Proteins/genetics; Ubiquitination; Ubiquitins/genetics; Ubiquitins/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Recombinant Fusion Proteins / Clathrin / ErbB Receptors Limits: Humans Language: En Journal: Traffic Journal subject: FISIOLOGIA Year: 2011 Type: Article Affiliation country: Norway

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google