Sequence and phenotypic analysis for resistance monitoring in hepatitis C virus drug development: recommendations from the HCV DRAG.

Kwong, Ann D; Najera, Isabel; Bechtel, Jill; Bowden, Scott; Fitzgibbon, Joseph; Harrington, Patrick; Kempf, Dale; Kieffer, Tara L; Koletzki, Diana; Kukolj, George; Lim, Sharlene; Pilot-Matias, Tami; Lin, Kai; Mani, Nina; Mo, Hongmei; O'Rear, Jules; Otto, Michael; Parkin, Neil; Pawlotsky, Jean-Michel; Petropoulos, Chris; Picchio, Gaston; Ralston, Robert; Reeves, Jacqueline D; Schooley, Robert T; Seiwert, Scott; Standring, David; Stuyver, Lieven; Sullivan, James; Miller, Veronica

Kwong, Ann D; Najera, Isabel; Bechtel, Jill; Bowden, Scott; Fitzgibbon, Joseph; Harrington, Patrick; Kempf, Dale; Kieffer, Tara L; Koletzki, Diana; Kukolj, George; Lim, Sharlene; Pilot-Matias, Tami; Lin, Kai; Mani, Nina; Mo, Hongmei; O'Rear, Jules; Otto, Michael; Parkin, Neil; Pawlotsky, Jean-Michel; Petropoulos, Chris; Picchio, Gaston; Ralston, Robert; Reeves, Jacqueline D; Schooley, Robert T; Seiwert, Scott; Standring, David; Stuyver, Lieven; Sullivan, James; Miller, Veronica.

Affiliation

Kwong AD; Vertex Pharmaceuticals, Inc, Cambridge, Massachusetts, USA.

Gastroenterology ; 140(3): 755-60, 2011 Mar.

Article in En | MEDLINE | ID: mdl-21255574

Subject(s)

Antiviral Agents/therapeutic use; Drug Discovery/standards; Drug Resistance, Viral/genetics; Hepacivirus/genetics; Hepatitis C/drug therapy; Genotype; Humans; Phenotype; Treatment Failure

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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Hepatitis C / Hepacivirus / Drug Resistance, Viral / Drug Discovery Type of study: Guideline Limits: Humans Language: En Journal: Gastroenterology Year: 2011 Type: Article Affiliation country: United States

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