Polymorphisms of hepatitis C virus non-structural protein 5A and core protein and clinical outcome of pegylated-interferon/ribavirin combination therapy.

El-Shamy, Ahmed; Kim, Soo-Ryang; Ide, Yoshi-Hiro; Sasase, Noriko; Imoto, Susumu; Deng, Lin; Shoji, Ikuo; Hotta, Hak

El-Shamy, Ahmed; Kim, Soo-Ryang; Ide, Yoshi-Hiro; Sasase, Noriko; Imoto, Susumu; Deng, Lin; Shoji, Ikuo; Hotta, Hak.

Affiliation

El-Shamy A; Division of Microbiology, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan.

Intervirology ; 55(1): 1-11, 2012.

Article in En | MEDLINE | ID: mdl-21293098

Subject(s)

Hepatitis C, Chronic/drug therapy; Hepatitis C, Chronic/virology; Interferon-alpha/administration & dosage; Polyethylene Glycols/administration & dosage; Polymorphism, Genetic; Ribavirin/administration & dosage; Viral Core Proteins/genetics; Viral Nonstructural Proteins/genetics; Aged; Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents/administration & dosage; Female; Hepacivirus/genetics; Hepacivirus/isolation & purification; Humans; Interferon alpha-2; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; RNA, Viral/genetics; Recombinant Proteins/administration & dosage; Sequence Analysis, DNA; Treatment Outcome

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Full text: 1 Database: MEDLINE Main subject: Polyethylene Glycols / Polymorphism, Genetic / Ribavirin / Viral Core Proteins / Interferon-alpha / Viral Nonstructural Proteins / Hepatitis C, Chronic Type of study: Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Intervirology Year: 2012 Type: Article Affiliation country: Japan

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