Role of unique basic residues in cytotoxic, antibacterial and antiparasitic activities of human eosinophil cationic protein.

Singh, Anubha; Batra, Janendra K

Singh, Anubha; Batra, Janendra K.

Affiliation

Singh A; Immunochemistry Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi, India.

Biol Chem ; 392(4): 337-46, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21303303

Subject(s)

Eosinophil Cationic Protein/chemistry; Eosinophil Cationic Protein/pharmacology; Amino Acid Sequence; Animals; Anti-Bacterial Agents/chemistry; Anti-Bacterial Agents/metabolism; Anti-Bacterial Agents/pharmacology; Antiparasitic Agents/chemistry; Antiparasitic Agents/metabolism; Antiparasitic Agents/pharmacology; Bacillus subtilis/drug effects; Biocatalysis; Cell Line; Cell Membrane/drug effects; Cell Membrane/metabolism; Cytotoxins/chemistry; Cytotoxins/genetics; Cytotoxins/metabolism; Cytotoxins/pharmacology; Eosinophil Cationic Protein/genetics; Eosinophil Cationic Protein/metabolism; Erythrocytes/cytology; Erythrocytes/drug effects; Escherichia coli/drug effects; Hemolysis/drug effects; Humans; Leishmania donovani/drug effects; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation

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Full text: 1 Database: MEDLINE Main subject: Eosinophil Cationic Protein Limits: Animals / Humans Language: En Journal: Biol Chem Journal subject: BIOQUIMICA Year: 2011 Type: Article Affiliation country: India

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