Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation.

Raven, Jennifer F; Williams, Virginie; Wang, Shuo; Tremblay, Michel L; Muller, William J; Durbin, Joan E; Koromilas, Antonis E

Raven, Jennifer F; Williams, Virginie; Wang, Shuo; Tremblay, Michel L; Muller, William J; Durbin, Joan E; Koromilas, Antonis E.

Affiliation

Raven JF; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec, Canada.

Cell Cycle ; 10(5): 794-804, 2011 Mar 01.

Article in En | MEDLINE | ID: mdl-21311224

Subject(s)

Cell Transformation, Neoplastic; Mammary Neoplasms, Experimental/metabolism; Receptor, ErbB-2/metabolism; STAT1 Transcription Factor/metabolism; Animals; Antineoplastic Agents/pharmacology; Cell Line; Chlorocebus aethiops; Disease Progression; Female; Gefitinib; Humans; Lapatinib; Mammary Glands, Animal/metabolism; Mammary Neoplasms, Experimental/pathology; Mice; Mice, Transgenic; Phosphorylation; Quinazolines/pharmacology; Receptor, ErbB-2/antagonists & inhibitors; Signal Transduction; Transplantation, Heterologous

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Database: MEDLINE Main subject: Cell Transformation, Neoplastic / Receptor, ErbB-2 / STAT1 Transcription Factor / Mammary Neoplasms, Experimental Limits: Animals / Female / Humans Language: En Journal: Cell Cycle Year: 2011 Type: Article Affiliation country: Canada

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