Identification and characterization of three novel small interference RNAs that effectively down-regulate the isolated nucleocapsid gene expression of SARS coronavirus.

Cao, Ying-Li; Wang, Ying; Guo, Rong; Yang, Fan; Zhang, Yun; Wang, Shu-Hui; Liu, Li

Cao, Ying-Li; Wang, Ying; Guo, Rong; Yang, Fan; Zhang, Yun; Wang, Shu-Hui; Liu, Li.

Affiliation

Cao YL; Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing 100005, China.

Molecules ; 16(2): 1544-58, 2011 Feb 11.

Article in En | MEDLINE | ID: mdl-21317844

Subject(s)

Gene Expression; Nucleocapsid Proteins/genetics; RNA, Small Interfering/metabolism; Severe acute respiratory syndrome-related coronavirus/genetics; Animals; Base Sequence; Cell Line; Chlorocebus aethiops; Down-Regulation; HEK293 Cells; Humans; Molecular Sequence Data; Nucleocapsid Proteins/metabolism; RNA, Small Interfering/genetics; Severe acute respiratory syndrome-related coronavirus/metabolism; Sequence Alignment; Vero Cells

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Full text: 1 Database: MEDLINE Main subject: Gene Expression / Nucleocapsid Proteins / RNA, Small Interfering / Severe acute respiratory syndrome-related coronavirus Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2011 Type: Article Affiliation country: China

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