Bone morphogenetic protein 2 signaling in osteoclasts is negatively regulated by the BMP antagonist, twisted gastrulation.

Pham, Lan; Beyer, Kayla; Jensen, Eric D; Rodriguez, Julio Sotillo; Davydova, Julia; Yamamoto, Masato; Petryk, Anna; Gopalakrishnan, Rajaram; Mansky, Kim C

Pham, Lan; Beyer, Kayla; Jensen, Eric D; Rodriguez, Julio Sotillo; Davydova, Julia; Yamamoto, Masato; Petryk, Anna; Gopalakrishnan, Rajaram; Mansky, Kim C.

Affiliation

Pham L; Department of Diagnostic and Biological Sciences, University of Minnesota School of Dentistry, Minneapolis, Minnesota 55455, USA.

J Cell Biochem ; 112(3): 793-803, 2011 Mar.

Article in En | MEDLINE | ID: mdl-21328453

Subject(s)

Bone Morphogenetic Protein 2/antagonists & inhibitors; Osteoclasts/cytology; Proteins/metabolism; Recombinant Proteins/metabolism; Signal Transduction; Adenoviridae/genetics; Animals; Apoptosis; Bone Morphogenetic Protein 2/metabolism; Cell Differentiation; Cell Proliferation; Cell Size; Down-Regulation; Gene Deletion; Genetic Vectors; Mice; Mice, 129 Strain; Mice, Knockout; Osteoclasts/virology; Proteins/genetics; RANK Ligand/pharmacology; Recombinant Proteins/genetics; Smad Proteins/metabolism

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Full text: 1 Database: MEDLINE Main subject: Osteoclasts / Recombinant Proteins / Signal Transduction / Proteins / Bone Morphogenetic Protein 2 Limits: Animals Language: En Journal: J Cell Biochem Year: 2011 Type: Article Affiliation country: United States

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