Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review.

Mandenius, Carl-Fredrik; Steel, Daniella; Noor, Fozia; Meyer, Thomas; Heinzle, Elmar; Asp, Julia; Arain, Sarina; Kraushaar, Udo; Bremer, Susanne; Class, Reiner; Sartipy, Peter

Mandenius, Carl-Fredrik; Steel, Daniella; Noor, Fozia; Meyer, Thomas; Heinzle, Elmar; Asp, Julia; Arain, Sarina; Kraushaar, Udo; Bremer, Susanne; Class, Reiner; Sartipy, Peter.

Affiliation

Mandenius CF; Biotechnology/IFM, Linköping University, Linköping, Sweden. cfm@ifm.liu.se

J Appl Toxicol ; 31(3): 191-205, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21328588

Subject(s)

Heart Diseases/chemically induced; Myocytes, Cardiac/drug effects; Pluripotent Stem Cells/drug effects; Xenobiotics/toxicity; Animal Testing Alternatives; Animals; Cell Differentiation; Cell Line, Transformed; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions/classification; Heart Diseases/pathology; Heart Diseases/physiopathology; Humans; Myocytes, Cardiac/metabolism; Myocytes, Cardiac/pathology; Oxygen Consumption; Pluripotent Stem Cells/cytology

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Full text: 1 Database: MEDLINE Main subject: Xenobiotics / Myocytes, Cardiac / Pluripotent Stem Cells / Heart Diseases Limits: Animals / Humans Language: En Journal: J Appl Toxicol Year: 2011 Type: Article Affiliation country: Sweden

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