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Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis.
Friede, T; Parsons, N; Stallard, N; Todd, S; Valdes Marquez, E; Chataway, J; Nicholas, R.
Affiliation
  • Friede T; Department of Medical Statistics, University Medical Center Göttingen, Germany. tim.friede@med.uni-goettingen.de
Stat Med ; 30(13): 1528-40, 2011 Jun 15.
Article in En | MEDLINE | ID: mdl-21341301
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Full text: 1 Database: MEDLINE Main subject: Models, Statistical / Clinical Trials, Phase III as Topic / Clinical Trials, Phase II as Topic / Multiple Sclerosis Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Stat Med Year: 2011 Type: Article Affiliation country: Germany
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Full text: 1 Database: MEDLINE Main subject: Models, Statistical / Clinical Trials, Phase III as Topic / Clinical Trials, Phase II as Topic / Multiple Sclerosis Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Stat Med Year: 2011 Type: Article Affiliation country: Germany