Depletion of the human N&#945;-terminal acetyltransferase A induces p53-dependent apoptosis and p53-independent growth inhibition.

Gromyko, Darina; Arnesen, Thomas; Ryningen, Anita; Varhaug, Jan Erik; Lillehaug, Johan R

Depletion of the human Nα-terminal acetyltransferase A induces p53-dependent apoptosis and p53-independent growth inhibition.

Gromyko, Darina; Arnesen, Thomas; Ryningen, Anita; Varhaug, Jan Erik; Lillehaug, Johan R.

Affiliation

Gromyko D; Department of Molecular Biology, University of Bergen, Bergen, Norway.

Int J Cancer ; 127(12): 2777-89, 2010 Dec 15.

Article in En | MEDLINE | ID: mdl-21351257

Subject(s)

Apoptosis; Arylamine N-Acetyltransferase/genetics; Isoenzymes/genetics; RNA Interference; Thyroid Neoplasms/enzymology; Thyroid Neoplasms/pathology; Tumor Suppressor Protein p53/metabolism; Blotting, Western; Carcinoma/enzymology; Carcinoma/genetics; Carcinoma/pathology; Carcinoma, Papillary/enzymology; Carcinoma, Papillary/genetics; Carcinoma, Papillary/pathology; Cell Cycle; Cell Differentiation; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Immunoenzyme Techniques; RNA, Messenger/genetics; RNA, Small Interfering/genetics; Reverse Transcriptase Polymerase Chain Reaction; Thyroid Neoplasms/genetics; Tumor Cells, Cultured; Tumor Suppressor Protein p53/genetics

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Full text: 1 Database: MEDLINE Main subject: Arylamine N-Acetyltransferase / Thyroid Neoplasms / Tumor Suppressor Protein p53 / Apoptosis / RNA Interference / Isoenzymes Limits: Humans Language: En Journal: Int J Cancer Year: 2010 Type: Article Affiliation country: Norway

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