HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production.

Harman, Andrew N; Lai, Joey; Turville, Stuart; Samarajiwa, Shamith; Gray, Lachlan; Marsden, Valerie; Mercier, Sarah K; Mercier, Sarah; Jones, Kate; Nasr, Najla; Rustagi, Arjun; Cumming, Helen; Donaghy, Heather; Mak, Johnson; Gale, Michael; Churchill, Melissa; Hertzog, Paul; Cunningham, Anthony L

Harman, Andrew N; Lai, Joey; Turville, Stuart; Samarajiwa, Shamith; Gray, Lachlan; Marsden, Valerie; Mercier, Sarah K; Mercier, Sarah; Jones, Kate; Nasr, Najla; Rustagi, Arjun; Cumming, Helen; Donaghy, Heather; Mak, Johnson; Gale, Michael; Churchill, Melissa; Hertzog, Paul; Cunningham, Anthony L.

Affiliation

Harman AN; Centre for Virus Research, Westmead Millennium Institute, Westmead, Australia.

Blood ; 118(2): 298-308, 2011 Jul 14.

Article in En | MEDLINE | ID: mdl-21411754

Subject(s)

Dendritic Cells/virology; HIV Infections/genetics; HIV Infections/immunology; HIV-1/physiology; Interferon Regulatory Factor-1/physiology; Interferon Type I/metabolism; Cells, Cultured; Dendritic Cells/metabolism; Dendritic Cells/pathology; Down-Regulation/immunology; Gene Expression Profiling; Gene Expression Regulation/immunology; HIV Infections/metabolism; HIV Infections/pathology; Humans; Interferon Regulatory Factor-1/genetics; Interferon Regulatory Factor-1/metabolism; Microarray Analysis; Promoter Regions, Genetic; Sequence Analysis, DNA; Signal Transduction/immunology; Signal Transduction/physiology; Up-Regulation/genetics; Up-Regulation/immunology

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Dendritic Cells / Interferon Type I / HIV Infections / HIV-1 / Interferon Regulatory Factor-1 Limits: Humans Language: En Journal: Blood Year: 2011 Type: Article Affiliation country: Australia

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google