Neuropsin cleaves EphB2 in the amygdala to control anxiety.

Attwood, Benjamin K; Bourgognon, Julie-Myrtille; Patel, Satyam; Mucha, Mariusz; Schiavon, Emanuele; Skrzypiec, Anna E; Young, Kenneth W; Shiosaka, Sadao; Korostynski, Michal; Piechota, Marcin; Przewlocki, Ryszard; Pawlak, Robert

Attwood, Benjamin K; Bourgognon, Julie-Myrtille; Patel, Satyam; Mucha, Mariusz; Schiavon, Emanuele; Skrzypiec, Anna E; Young, Kenneth W; Shiosaka, Sadao; Korostynski, Michal; Piechota, Marcin; Przewlocki, Ryszard; Pawlak, Robert.

Affiliation

Attwood BK; Department of Cell Physiology and Pharmacology, University of Leicester, University Road, Leicester LE1 9HN, UK.

Nature ; 473(7347): 372-5, 2011 May 19.

Article in En | MEDLINE | ID: mdl-21508957

Subject(s)

Amygdala/metabolism; Anxiety/metabolism; Kallikreins/metabolism; Receptor, EphB2/metabolism; Amygdala/cytology; Animals; Anxiety/genetics; Anxiety Disorders/etiology; Anxiety Disorders/genetics; Anxiety Disorders/metabolism; Electric Conductivity; Fear; Gene Expression Regulation; Kallikreins/deficiency; Kallikreins/genetics; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neurons/metabolism; Protein Binding; Receptor, EphB2/chemistry; Receptors, N-Methyl-D-Aspartate/chemistry; Receptors, N-Methyl-D-Aspartate/metabolism; Stress, Psychological/metabolism; Tacrolimus Binding Proteins/genetics

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Full text: 1 Database: MEDLINE Main subject: Anxiety / Kallikreins / Receptor, EphB2 / Amygdala Type of study: Etiology_studies / Risk_factors_studies Limits: Animals Language: En Journal: Nature Year: 2011 Type: Article Affiliation country: United kingdom

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