The oncogenic PIM kinase family regulates drug resistance through multiple mechanisms.

Isaac, Methvin; Siu, Allan; Jongstra, Jan

Isaac, Methvin; Siu, Allan; Jongstra, Jan.

Affiliation

Isaac M; Medicinal Chemistry Platform, Ontario Institute for Cancer Research, Toronto, Canada.

Drug Resist Updat ; 14(4-5): 203-11, 2011.

Article in En | MEDLINE | ID: mdl-21601509

Subject(s)

Drug Resistance, Neoplasm/physiology; Neoplasm Proteins/physiology; Proto-Oncogene Proteins c-pim-1/physiology; Animals; Antineoplastic Agents/metabolism; Antineoplastic Agents/pharmacology; Humans; Mice; Molecular Targeted Therapy; Neoplasm Proteins/drug effects; Neoplasms/drug therapy; Neoplasms/metabolism; Neoplasms/physiopathology; Protein Kinase Inhibitors/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Drug Resistance, Neoplasm / Proto-Oncogene Proteins c-pim-1 / Neoplasm Proteins Limits: Animals / Humans Language: En Journal: Drug Resist Updat Journal subject: ANTINEOPLASICOS Year: 2011 Type: Article Affiliation country: Canada

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