Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment.

Schmitz, Maike; Breithaupt, Petra; Scheidegger, Nastassja; Cario, Gunnar; Bonapace, Laura; Meissner, Barbara; Mirkowska, Paulina; Tchinda, Joelle; Niggli, Felix K; Stanulla, Martin; Schrappe, Martin; Schrauder, Andre; Bornhauser, Beat C; Bourquin, Jean-Pierre

Schmitz, Maike; Breithaupt, Petra; Scheidegger, Nastassja; Cario, Gunnar; Bonapace, Laura; Meissner, Barbara; Mirkowska, Paulina; Tchinda, Joelle; Niggli, Felix K; Stanulla, Martin; Schrappe, Martin; Schrauder, Andre; Bornhauser, Beat C; Bourquin, Jean-Pierre.

Affiliation

Schmitz M; Division of Oncology and Children's Research Center, University Children's Hospital, University of Zurich, Zurich, Switzerland.

Blood ; 118(7): 1854-64, 2011 Aug 18.

Article in En | MEDLINE | ID: mdl-21670474

Subject(s)

Phenotype; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/genetics; Animals; Antineoplastic Agents/therapeutic use; Clone Cells; Cyclin-Dependent Kinase Inhibitor p16/genetics; Gene Deletion; Gene Dosage; Gene Rearrangement; Gene Rearrangement, T-Lymphocyte; Genes, Immunoglobulin; Humans; Mice; Neoplasm, Residual; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy; Transplantation, Heterologous; Tumor Cells, Cultured

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Full text: 1 Database: MEDLINE Main subject: Phenotype / Precursor B-Cell Lymphoblastic Leukemia-Lymphoma Limits: Animals / Humans Language: En Journal: Blood Year: 2011 Type: Article Affiliation country: Switzerland

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