Molecular profiling of direct xenograft tumors established from human pancreatic adenocarcinoma after neoadjuvant therapy.

Kim, Michael P; Truty, Mark J; Choi, Woonyoung; Kang, Ya'an; Chopin-Lally, Xavier; Gallick, Gary E; Wang, Huamin; McConkey, David J; Hwang, Rosa; Logsdon, Craig; Abbruzzesse, James; Fleming, Jason B

Kim, Michael P; Truty, Mark J; Choi, Woonyoung; Kang, Ya'an; Chopin-Lally, Xavier; Gallick, Gary E; Wang, Huamin; McConkey, David J; Hwang, Rosa; Logsdon, Craig; Abbruzzesse, James; Fleming, Jason B.

Affiliation

Kim MP; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Ann Surg Oncol ; 19 Suppl 3: S395-403, 2012 Jul.

Article in En | MEDLINE | ID: mdl-21701930

Subject(s)

Adenocarcinoma/genetics; Insulin-Like Growth Factor Binding Protein 3/genetics; Pancreatic Neoplasms/genetics; Protein Serine-Threonine Kinases/genetics; RNA, Messenger/metabolism; Receptors, Transforming Growth Factor beta/genetics; Adenocarcinoma/drug therapy; Adenocarcinoma/metabolism; Animals; Drug Resistance, Neoplasm/genetics; Gene Expression Profiling; Humans; Insulin-Like Growth Factor Binding Protein 3/metabolism; Mice; Mice, Inbred NOD; Mice, SCID; Neoadjuvant Therapy; Pancreatic Neoplasms/drug therapy; Pancreatic Neoplasms/metabolism; Protein Serine-Threonine Kinases/metabolism; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta/metabolism; Transplantation, Heterologous

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Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / RNA, Messenger / Adenocarcinoma / Protein Serine-Threonine Kinases / Receptors, Transforming Growth Factor beta / Insulin-Like Growth Factor Binding Protein 3 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Ann Surg Oncol Journal subject: NEOPLASIAS Year: 2012 Type: Article Affiliation country: United States

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