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Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens.
Wyen, Christoph; Hendra, Heidy; Siccardi, Marco; Platten, Martin; Jaeger, Hans; Harrer, Thomas; Esser, Stefan; Bogner, Johannes R; Brockmeyer, Norbert H; Bieniek, Bernhard; Rockstroh, Juergen; Hoffmann, Christian; Stoehr, Albrecht; Michalik, Claudia; Dlugay, Verena; Jetter, Alexander; Knechten, Heribert; Klinker, Hartwig; Skaletz-Rorowski, Adriane; Fätkenheuer, Gerd; Egan, Deirdre; Back, David J; Owen, Andrew.
Affiliation
  • Wyen C; Department of Internal Medicine, University of Cologne, Cologne, Germany.
J Antimicrob Chemother ; 66(9): 2092-8, 2011 Sep.
Article in En | MEDLINE | ID: mdl-21715435
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Full text: 1 Database: MEDLINE Main subject: Oxidoreductases, N-Demethylating / Polymorphism, Genetic / Aryl Hydrocarbon Hydroxylases / Receptors, Cytoplasmic and Nuclear / Anti-HIV Agents / Benzoxazines Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: J Antimicrob Chemother Year: 2011 Type: Article Affiliation country: Germany
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Full text: 1 Database: MEDLINE Main subject: Oxidoreductases, N-Demethylating / Polymorphism, Genetic / Aryl Hydrocarbon Hydroxylases / Receptors, Cytoplasmic and Nuclear / Anti-HIV Agents / Benzoxazines Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: J Antimicrob Chemother Year: 2011 Type: Article Affiliation country: Germany