VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sprouting.

Oladipupo, Sunday; Hu, Song; Kovalski, Joanna; Yao, Junjie; Santeford, Andrea; Sohn, Rebecca E; Shohet, Ralph; Maslov, Konstantin; Wang, Lihong V; Arbeit, Jeffrey M

Oladipupo, Sunday; Hu, Song; Kovalski, Joanna; Yao, Junjie; Santeford, Andrea; Sohn, Rebecca E; Shohet, Ralph; Maslov, Konstantin; Wang, Lihong V; Arbeit, Jeffrey M.

Affiliation

Oladipupo S; Urology Division, Department of Surgery, and Department of Medicine, University of Hawaii 96813, USA.

Proc Natl Acad Sci U S A ; 108(32): 13264-9, 2011 Aug 09.

Article in En | MEDLINE | ID: mdl-21784979

Subject(s)

Endothelial Cells/metabolism; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Neovascularization, Pathologic/metabolism; Vascular Endothelial Growth Factor A/metabolism; Animals; Cell Proliferation/drug effects; Endothelial Cells/drug effects; Epithelial Cells/drug effects; Epithelial Cells/metabolism; Epithelial Cells/pathology; Gene Deletion; Integrases/metabolism; Keratinocytes/drug effects; Keratinocytes/metabolism; Mice; Microvessels/drug effects; Microvessels/pathology; Myeloid Cells/metabolism; Myeloid Cells/pathology; Neovascularization, Pathologic/genetics; Tetracycline/pharmacology; Tetradecanoylphorbol Acetate/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Endothelial Cells / Vascular Endothelial Growth Factor A / Hypoxia-Inducible Factor 1, alpha Subunit / Neovascularization, Pathologic Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2011 Type: Article Affiliation country: United States

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