Activation of Akt/GSK3ß and Akt/Bcl-2 signaling pathways in nickel-transformed BEAS-2B cells.

Pan, Jing-Ju; Chang, Qing-Shan; Wang, Xin; Son, Young-Ok; Liu, Jiankang; Zhang, Zhuo; Bi, Yong-Yi; Shi, Xianglin

Pan, Jing-Ju; Chang, Qing-Shan; Wang, Xin; Son, Young-Ok; Liu, Jiankang; Zhang, Zhuo; Bi, Yong-Yi; Shi, Xianglin.

Affiliation

Pan JJ; Institute of Chronic Non-Communicable Disease, Hubei Provincial Center for Disease Control and Prevention, Wuhan 430079, P.R. China.

Int J Oncol ; 39(5): 1285-94, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21837363

Subject(s)

Carcinogens/pharmacology; Epithelial Cells/drug effects; Glycogen Synthase Kinase 3/metabolism; Nickel/pharmacology; Proto-Oncogene Proteins c-akt/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; Signal Transduction; Cell Line, Transformed; Cell Transformation, Neoplastic/drug effects; Down-Regulation/drug effects; Enzyme Activation/drug effects; Epithelial Cells/metabolism; Epithelial Cells/pathology; Glycogen Synthase Kinase 3 beta; Humans; Mitogen-Activated Protein Kinases/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Reactive Oxygen Species/metabolism; Retinoblastoma Protein/metabolism; Signal Transduction/drug effects; Tumor Suppressor Protein p53/metabolism; Up-Regulation/drug effects

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Full text: 1 Database: MEDLINE Main subject: Carcinogens / Signal Transduction / Proto-Oncogene Proteins c-bcl-2 / Glycogen Synthase Kinase 3 / Epithelial Cells / Proto-Oncogene Proteins c-akt / Nickel Limits: Humans Language: En Journal: Int J Oncol Journal subject: NEOPLASIAS Year: 2011 Type: Article

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