RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element.

Levantini, Elena; Lee, Sanghoon; Radomska, Hanna S; Hetherington, Christopher J; Alberich-Jorda, Meritxell; Amabile, Giovanni; Zhang, Pu; Gonzalez, David A; Zhang, Junyan; Basseres, Daniela S; Wilson, Nicola K; Koschmieder, Steffen; Huang, Gang; Zhang, Dong-Er; Ebralidze, Alexander K; Bonifer, Constanze; Okuno, Yutaka; Gottgens, Bertie; Tenen, Daniel G

Levantini, Elena; Lee, Sanghoon; Radomska, Hanna S; Hetherington, Christopher J; Alberich-Jorda, Meritxell; Amabile, Giovanni; Zhang, Pu; Gonzalez, David A; Zhang, Junyan; Basseres, Daniela S; Wilson, Nicola K; Koschmieder, Steffen; Huang, Gang; Zhang, Dong-Er; Ebralidze, Alexander K; Bonifer, Constanze; Okuno, Yutaka; Gottgens, Bertie; Tenen, Daniel G.

Affiliation

Levantini E; Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, Center for Life Science, Boston, MA, USA. elevanti@bidmc.harvard.edu

EMBO J ; 30(19): 4059-70, 2011 Aug 26.

Article in En | MEDLINE | ID: mdl-21873977

Subject(s)

Antigens, CD34/metabolism; Core Binding Factor Alpha 2 Subunit/genetics; Gene Expression Regulation; Hematopoietic Stem Cells/metabolism; Animals; Bone Marrow Transplantation; Chromatin/metabolism; Core Binding Factor Alpha 2 Subunit/metabolism; Fetal Blood/cytology; Genotype; HL-60 Cells; Humans; Mice; Mice, Transgenic; Models, Biological; Regulatory Sequences, Nucleic Acid/genetics

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Full text: 1 Database: MEDLINE Main subject: Hematopoietic Stem Cells / Gene Expression Regulation / Antigens, CD34 / Core Binding Factor Alpha 2 Subunit Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: EMBO J Year: 2011 Type: Article Affiliation country: United States

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