Regression of established hepatocellular carcinoma is induced by chemoimmunotherapy in an orthotopic murine model.

Avella, Diego M; Li, Guangfu; Schell, Todd D; Liu, Dai; Zhang, Samuel Shao-Min; Lou, Xi; Berg, Arthur; Kimchi, Eric T; Tagaram, Hephzibah Rani S; Yang, Qing; Shereef, Serene; Garcia, Luis S; Kester, Mark; Isom, Harriet C; Rountree, C Bart; Staveley-O'Carroll, Kevin F

Avella, Diego M; Li, Guangfu; Schell, Todd D; Liu, Dai; Zhang, Samuel Shao-Min; Lou, Xi; Berg, Arthur; Kimchi, Eric T; Tagaram, Hephzibah Rani S; Yang, Qing; Shereef, Serene; Garcia, Luis S; Kester, Mark; Isom, Harriet C; Rountree, C Bart; Staveley-O'Carroll, Kevin F.

Affiliation

Avella DM; Department of Surgery, Division of Surgical Oncology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

Hepatology ; 55(1): 141-52, 2012 Jan.

Article in En | MEDLINE | ID: mdl-21898502

Subject(s)

Adoptive Transfer/methods; Antineoplastic Agents/pharmacology; Carcinoma, Hepatocellular/drug therapy; Indoles/pharmacology; Liver Neoplasms/drug therapy; Pyrroles/pharmacology; Adenocarcinoma/drug therapy; Adenocarcinoma/immunology; Adenocarcinoma/pathology; Animals; CD8-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/transplantation; Carcinoma, Hepatocellular/immunology; Carcinoma, Hepatocellular/pathology; Combined Modality Therapy; Disease Models, Animal; Hep G2 Cells; Hepatocytes/immunology; Hepatocytes/transplantation; Humans; Immune Tolerance/immunology; Immunocompetence/immunology; Liver Neoplasms/immunology; Liver Neoplasms/pathology; Mice; Mice, Inbred C57BL; Mice, Transgenic; STAT3 Transcription Factor/immunology; STAT3 Transcription Factor/metabolism; Sunitinib

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Full text: 1 Database: MEDLINE Main subject: Pyrroles / Carcinoma, Hepatocellular / Adoptive Transfer / Indoles / Liver Neoplasms / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Hepatology Year: 2012 Type: Article Affiliation country: United States

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