An influenza N1 neuraminidase-specific  monoclonal antibody with broad neuraminidase  inhibition activity against H5N1 HPAI viruses.

Shoji, Yoko; Chichester, Jessica A; Palmer, Gene A; Farrance, Christine E; Stevens, Robert; Stewart, Michelle; Goldschmidt, Lauren; Deyde, Varough; Gubareva, Larisa; Klimov, Alexander; Mett, Vadim; Yusibov, Vidadi

An influenza N1 neuraminidase-specific monoclonal antibody with broad neuraminidase inhibition activity against H5N1 HPAI viruses.

Shoji, Yoko; Chichester, Jessica A; Palmer, Gene A; Farrance, Christine E; Stevens, Robert; Stewart, Michelle; Goldschmidt, Lauren; Deyde, Varough; Gubareva, Larisa; Klimov, Alexander; Mett, Vadim; Yusibov, Vidadi.

Affiliation

Shoji Y; Fraunhofer USA Center for Molecular Biotechnology, Newark, DE, USA.

Hum Vaccin ; 7 Suppl: 199-204, 2011.

Article in En | MEDLINE | ID: mdl-21922687

Subject(s)

Antibodies, Monoclonal/immunology; Antibodies, Neutralizing/immunology; Antibodies, Viral/immunology; Influenza A Virus, H5N1 Subtype/immunology; Neuraminidase/immunology; Orthomyxoviridae Infections/prevention & control; Viral Proteins/immunology; Animals; Antibodies, Monoclonal/administration & dosage; Antibodies, Neutralizing/administration & dosage; Antibodies, Viral/administration & dosage; Body Weight; Disease Models, Animal; Female; Male; Mice; Mice, Inbred BALB C; Rodent Diseases/prevention & control; Survival Analysis

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Database: MEDLINE Main subject: Viral Proteins / Orthomyxoviridae Infections / Influenza A Virus, H5N1 Subtype / Antibodies, Neutralizing / Antibodies, Monoclonal / Antibodies, Viral / Neuraminidase Limits: Animals Language: En Journal: Hum Vaccin Journal subject: ALERGIA E IMUNOLOGIA Year: 2011 Type: Article Affiliation country: United States

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