Three-dimensional nonlinear microspectroscopy and imaging of soft condensed matter.
Opt Lett
; 36(19): 3849-51, 2011 Oct 01.
Article
in En
| MEDLINE
| ID: mdl-21964118
ABSTRACT
We report on the realization of a sensitive microspectroscopy and imaging approach based on a three-color femtosecond coherent anti-Stokes Raman scattering (CARS) technique with high spectral, time, and spatial resolution. Independently tunable, high-repetition rate optical parametric oscillators were used to attain a dynamic range of 5 orders of magnitude for time-domain CARS signal. The attained sensitivity permitted tracing the decay of weak and structurally complex Raman active modes in soft condensed matter. Application of this approach to imaging of the biological specimen shows a great potential in quantitative characterization of live biological media with an ability to access inter- and intra-molecular interactions.
Full text:
1
Database:
MEDLINE
Main subject:
Spectrum Analysis, Raman
/
Imaging, Three-Dimensional
/
Erythrocytes
/
Microscopy
Limits:
Humans
Language:
En
Journal:
Opt Lett
Year:
2011
Type:
Article
Affiliation country:
United States