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The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism.
Eudy, Rena J; Sahasrabudhe, Vaishali; Sweeney, Kevin; Tugnait, Meera; King-Ahmad, Amanda; Near, Kristen; Loria, Paula; Banker, Mary Ellen; Piotrowski, David W; Boustany-Kari, Carine M.
Affiliation
  • Eudy RJ; Department of Cardiovascular, Metabolic, and Endocrine Diseases, Pfizer, Eastern Point Road, Groton, CT, USA.
J Transl Med ; 9: 180, 2011 Oct 21.
Article in En | MEDLINE | ID: mdl-22017794
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Full text: 1 Database: MEDLINE Main subject: Potassium / Sodium / Aldosterone / Mineralocorticoid Receptor Antagonists / Translational Research, Biomedical Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Animals / Humans / Male Language: En Journal: J Transl Med Year: 2011 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Potassium / Sodium / Aldosterone / Mineralocorticoid Receptor Antagonists / Translational Research, Biomedical Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Animals / Humans / Male Language: En Journal: J Transl Med Year: 2011 Type: Article Affiliation country: United States