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De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.
Kirov, G; Pocklington, A J; Holmans, P; Ivanov, D; Ikeda, M; Ruderfer, D; Moran, J; Chambert, K; Toncheva, D; Georgieva, L; Grozeva, D; Fjodorova, M; Wollerton, R; Rees, E; Nikolov, I; van de Lagemaat, L N; Bayés, A; Fernandez, E; Olason, P I; Böttcher, Y; Komiyama, N H; Collins, M O; Choudhary, J; Stefansson, K; Stefansson, H; Grant, S G N; Purcell, S; Sklar, P; O'Donovan, M C; Owen, M J.
Affiliation
  • Kirov G; Department of Psychological Medicine and Neurology, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK. kirov@cardiff.ac.uk
Mol Psychiatry ; 17(2): 142-53, 2012 Feb.
Article in En | MEDLINE | ID: mdl-22083728
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Full text: 1 Database: MEDLINE Main subject: Schizophrenia / Synapses / Genetic Predisposition to Disease / DNA Copy Number Variations Type of study: Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Limits: Female / Humans / Male Country/Region as subject: Asia / Europa Language: En Journal: Mol Psychiatry Journal subject: BIOLOGIA MOLECULAR / PSIQUIATRIA Year: 2012 Type: Article Affiliation country: United kingdom
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Full text: 1 Database: MEDLINE Main subject: Schizophrenia / Synapses / Genetic Predisposition to Disease / DNA Copy Number Variations Type of study: Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Limits: Female / Humans / Male Country/Region as subject: Asia / Europa Language: En Journal: Mol Psychiatry Journal subject: BIOLOGIA MOLECULAR / PSIQUIATRIA Year: 2012 Type: Article Affiliation country: United kingdom